In Vitro Maturation (IVM)

A fertility treatment that allows eggs to mature outside the body in a laboratory setting, offering a gentler alternative to traditional IVF. IVM is particularly suitable for women who cannot or should not undergo full hormonal stimulation, providing a safe and effective path to parenthood.

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In vitro maturation (IVM) procedure at Genesis Athens fertility clinic.

What is In Vitro Maturation (IVM)?

In Vitro Maturation (IVM) is a fertility treatment in which immature eggs are collected from the ovaries and matured in a controlled laboratory environment before fertilisation. Unlike conventional IVF, IVM does not require extensive hormonal stimulation, making it a suitable option for women at risk of ovarian hyperstimulation syndrome (OHSS) or those with polycystic ovary syndrome (PCOS).

At Genesis Athens, the collected eggs are matured under carefully monitored laboratory conditions and then fertilised using In Vitro Fertilization (IVF) techniques. The resulting embryos are cultured and transferred to the uterus, offering a safer and less invasive path to conception.

What is In Vitro Maturation (IVM)?

Woman at high risk of ovarian hyperstimulation syndrome considering in vitro maturation (IVM).

Women who are at high risk of ovarian hyperstimulation syndrome (OHSS).

Patient advised against full hormonal stimulation for medical reasons choosing IVM treatment.

Patients who cannot undergo full hormonal stimulation for medical reasons.

Woman with polycystic ovary syndrome (PCOS) considering IVM for safer fertility treatment.

Women with polycystic ovary syndrome (PCOS) who may respond unpredictably to stimulation.

Treatment steps

Your step-by-step guide to In Vitro Maturation (IVM)

Every treatment at Genesis follows a structured, personalised process designed to support you medically and emotionally at every stage. From the first consultation to post-treatment care, we are here to guide you with clarity, expertise, and compassion. While each treatment has its own clinical steps, the journey always begins with understanding your individual needs and building a plan that gives you the best possible chance of success.

Blastocyst Transfer

Your fertility specialist will assess whether IVM is a suitable approach for you based on your medical history, hormonal profile, and ovarian reserve.

You will either receive a short course of low-dose hormones or no medication at all, depending on your protocol. The goal is to collect immature eggs directly from your ovaries.

Immature eggs are retrieved via a short procedure under light sedation. The eggs are then matured in our laboratory over the following 24–48 hours.

Once the eggs have matured, they are fertilised using ICSI or IVF. Embryos are then cultured for several days before selection.

A healthy embryo is transferred to the uterus during a simple, pain-free procedure. Remaining embryos can be frozen for future use.

A blood test is performed approximately two weeks after transfer to check for pregnancy.

Patient Journey

Your pathway to parenthood with us

At Genesis, every fertility journey is deeply personal. We understand the emotional and medical challenges involved, which is why our team is here to support you with care, expertise, and understanding — every step of the way.

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Call our team and let us guide you through the first steps of your fertility journey with kindness, clarity, and full support.

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Book a consultation

Meet with a specialist to review your results and receive clear, personalised guidance on your next steps.

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Define your treatment

Your fertility plan will be built around your needs, giving you the best chance of success with care that truly fits you.

Our treatments

Every journey is different

No two paths are alike. We keep you informed and supported with answers and care tailored to your experience.

Our fertility processes

F.A.Q.

In Vitro Maturation (IVM) F.A.Q.

We know that starting fertility treatment often comes with many questions — about the process, the risks, and what to expect. In this section, we address some of the most common concerns to help you feel more confident and informed.

If you do not see your question here, our team is always available to provide further guidance, personalised to your specific situation.

In IVF, eggs mature inside the body through hormone stimulation. In IVM, immature eggs are collected early and matured in the lab before fertilisation.

Yes. IVM avoids the risks associated with high-dose hormone stimulation, making it safer for patients prone to complications like OHSS.

IVM may have slightly lower success rates than conventional IVF, but it is an effective and safer alternative for the right patients.

Yes. Matured and fertilised embryos from IVM can be frozen for future use, just like with standard IVF.

No. The egg collection procedure is performed under sedation and is typically well tolerated, with minimal recovery time.

IVM is not recommended for patients who require high egg yield or who may benefit more from a full IVF protocol. Your doctor will advise based on your specific case.

Get in touch with an expert

Talk to an expert about 
In Vitro Maturation (IVM)

If you have any questions about In Vitro Maturation (IVM) or if you’re concerned about your fertility, our friendly patient support team is here to provide the support and guidance you need.

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Success Stories

Results that bring happiness to birth

Behind every success is a unique story of hope, strength, and care. At Genesis Athens, we are honoured to be part of the journeys that lead to new beginnings. From first consultations to the moment a child is born, our team stands beside each individual and couple with expertise, empathy, and dedication. Discover real experiences from patients who turned their dreams into reality — guided by the care, science, and support they found at Genesis.